Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 Powder
A dual-peptide powder for cosmetic formulations targeting the appearance of fine lines, skin texture and firmness. Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 are widely discussed in cosmetic peptide research and used together in anti-aging skin-care systems.
This combination is an ingredient option for formulators developing peptide facial serums, daily moisturizers and eye-care products. Its appeal is a targeted peptide approach to visible skin aging, allowing the finished formula to combine fine-line-focused care with the hydration, texture and skin feel supplied by the rest of the formula.
What Are Palmitoylated Peptides?
Peptides are short chains of amino acids. In these ingredients, a palmitoyl fatty-acid group is attached to the peptide structure. Palmitoylation changes a peptide's physical properties and is a design approach used in topical cosmetic ingredients.
Palmitoyl Tripeptide-1 is a signal peptide studied in relation to the extracellular matrix, the network of proteins and other substances surrounding skin cells. Research examines its effects on matrix components such as collagen and fibronectin. For cosmetic formulation, this makes it relevant to products focused on smoother-looking skin and the appearance of firmness.
Palmitoyl Tetrapeptide-7 is a complementary palmitoylated peptide investigated in skin-aging research. Together, the pair has been studied in cosmetic systems aimed at improving the visible appearance of aging skin.
Benefits and Formulation Applications
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Fine-line care: For serums and creams developed to address the visible appearance of fine lines.
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Texture-focused skin care: For products targeting a smoother, more refined-looking complexion.
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Firmness-focused moisturizers: A peptide ingredient direction for facial and neck-care formulations.
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Eye-care formulations: The combination has been investigated in multi-ingredient eye creams.
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Daily peptide routines: Suitable as a formulation concept for leave-on cosmetic serums and moisturizers.
Formulation Details
| Property |
Detail |
| Peptide ingredient names |
Palmitoyl Tripeptide-1; Palmitoyl Tetrapeptide-7 |
| Ingredient type |
Palmitoylated cosmetic peptides |
| Product format |
Powder |
| Palmitoyl Tripeptide-1 CAS |
147732-56-7 |
| Palmitoyl Tetrapeptide-7 CAS |
221227-05-0 |
| Applications |
Facial serums, moisturizers, eye-care products and fine-line-focused cosmetics |
Formulating With Peptide Powder
Calculate addition on an active-peptide basis using the powder's composition and peptide ratio. Powder and diluted liquid peptide ingredients have different concentrations, so their addition rates are not interchangeable.
For a serum, build around the desired hydration and skin feel with an appropriate humectant and thickening system. For a cream, combine the peptide system with a suitable moisturizing base. Select the incorporation method, working pH and processing conditions for the exact grade being used.
Use accurate weighing and uniform incorporation throughout the batch. Include an appropriate preservation system in water-containing products and complete stability, preservation and packaging testing as part of finished-product development.
Research Background
A 2025 peer-reviewed review discusses this peptide combination in anti-aging cosmetic systems. A 2024 study of an eye cream containing both peptides and additional actives reported improvements in several skin measures over 12 weeks. These findings support the formulation interest in the pair; results are specific to the complete products studied.
Cosmetic Use
For incorporation into finished cosmetic formulations, not direct application of undiluted powder. Follow material-specific handling and storage instructions.
Further Reading
Cosmetic peptide review (2025) | Multi-component eye cream study (2024)
